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A multiplex assay for the sensitive detection and quantification of male and female Plasmodium falciparum gametocytes

29 Nov 2018

Abstract excerpt

The transmission of malaria to mosquitoes depends on the presence of gametocytes that circulate in the peripheral blood of infected human hosts. Sensitive estimates of the densities of female gametocytes (FG) and male gametocytes (MG) may allow the prediction of infectivity to mosquitoes and thus a molecular estimate of the human infectious reservoir for transmission. A novel multiplex qRT-PCR assay with...

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PMID: 30497508
DOI: 10.1186/s12936-018-2584-y

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