Radical surgical resection with molecular margins is associated with improved survival in IDH wild-type glioblastoma.

doi:10.1093/neuonc/noae073

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Article

Radical surgical resection with molecular margins is associated with improved survival in IDH wild-type glioblastoma.

Neuro-oncology - 5 Sept 2024

Massaad Elie, Smith William J, Bradley Joseph, Esposito Eric, Gupta Mihir, Burns Evan, Burns Ryan, Velarde José K, Berglar Inka K, Gupta Rajiv, Martinez-Lage Maria, Dietrich Jorg, Lennerz Jochen K, Dunn Gavin P, Jones Pamela S, Choi Bryan D, Kim Albert E, Frosch Matthew, Barker Fred G, Curry William T, Carter Bob S, Nahed Brian V, Cahill Daniel P, Shankar Ganesh M

Abstract excerpt

BACKGROUND: Survival is variable in patients with glioblastoma IDH wild-type (GBM), even after comparable surgical resection of radiographically detectable disease, highlighting the limitations of radiographic assessment of infiltrative tumor anatomy. The majority of postsurgical progressive events are failures within 2 cm of the resection margin, motivating supramaximal resection strategies to improve local...

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Identifiers

PMID: 38581292
DOI: 10.1093/neuonc/noae073
PMCID: PMC11376447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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