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Article

Clinicopathologic analysis of microscopic tumor extension in glioma for external beam radiotherapy planning.

BMC medicine - 17 Nov 2021

Nie Shulun, Zhu Yufang, Yang Jia, Xin Tao, Xue Song, Sun Jujie, Mu Dianbin, Chen Zhaoqiu, Sun Pengpeng, Yu Jinming, Hu Man

Abstract excerpt

BACKGROUND: There is no consensus regarding the clinical target volume (CTV) margins in radiotherapy for glioma. In this study, we aimed to perform a complete macropathologic analysis examining microscopic tumor extension (ME) to more accurately define the CTV in glioma. METHODS: Thirty-eight supra-total resection specimens of glioma patients were examined on histologic sections. The ME distance, defined as the...

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Identifiers

PMID: 34784919
DOI: 10.1186/s12916-021-02143-w
PMCID: PMC8597244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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