Article
The Impact of Extensive Surgical Resection of Butterfly Glioblastomas on Outcomes in the Presence of TERT Mutation and EGFR Amplification: A Retrospective Cohort Study.
Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2000
Hekimoglu Mehdi, Basak Ahmet Tulgar, Akgun Mehmet Yigit, Ozer Hıdır, Ozgen Utku, Maleki Raha, Saban Dina, Oktenoğlu Tunc, Ozer Ali Fahir, Sasani Mehdi
Abstract excerpt
BACKGROUND AND OBJECTIVES: This study aimed to assess if extensive surgical resection enhances outcomes in wild-type Isocitrate Dehydrogenase (IDH) butterfly glioblastoma (B-GBM) patients, despite the presence of Telomerase Reverse Transcriptase (TERT) mutation and Epidermal Growth Factor Receptor (EGFR) amplification. METHODS: The study, retrospectively conducted from 2014 to 2022, involved 723 GBM patients, 41...
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