Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor.

Cancer medicine - 1 Sept 2018

Franklin Miriam, Gentles Lucy, Matheson Elizabeth, Bown Nick, Cross Paul, Ralte Angela, Gilkes-Immeson Connor, Bradbury Alice, Zanjirband Maryam, Lunec John, Drew Yvette, O'Donnell Rachel, Curtin Nicola J

Abstract excerpt

NUCOLL43 is a novel ovarian clear cell carcinoma (O-CCC) cell line that arose from a primary culture of a patient's malignant ascites. The cells grow reliably in cell culture with a doubling time of approx. 45 hours and form colonies at high efficiency. They have a very high degree of loss of heterozygosity (LOH) affecting approximately 85% of the genome, mostly copy neutral and almost identical to the original...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma, Clear Cell
Share to Biopsy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Genomics

Share to Ovarian Neoplasms

Share to Pharmacogenomic Variants

Share to Recombinational DNA Repair

Share to Tomography, X-Ray Computed

Source

Open in PubMed Open full text

Identifiers

PMID: 30109783
DOI: 10.1002/cam4.1724
PMCID: PMC6144150

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor.PMID 30109783Read ↗

A clear cancer cell line (150057) derived from human endometrial carcinoma harbors two novel mutations.Semantic proximity Read ↗

Characterization of Mutational Status, Spheroid Formation, and Drug Response of a New Genomically-Stable Human Ovarian Clear Cell Carcinoma Cell Line, 105C.Semantic proximity Read ↗

Molecular portraits of clear cell ovarian and endometrial carcinoma with comparison to clear cell renal cell carcinoma.Semantic proximity Read ↗

Translational genomics of ovarian clear cell carcinoma.Semantic proximity Read ↗

Ovarian Clear Cell Carcinoma: Genomic Characterization, Pathogenesis and Targeted TherapySemantic proximity Read ↗

Clear Cell Carcinoma of Uterine Cervix: A Clinicopathologic Review and Molecular CharacterizationSemantic proximity Read ↗

Functional characterisation of a novel ovarian cancer cell line, NUOC-1.Semantic proximity Read ↗

Targeting DNA Damage Response Pathway in Ovarian Clear Cell CarcinomaSemantic proximity Read ↗

Review the progression of ovarian clear cell carcinoma from the perspective of genomics and epigenomicsSemantic proximity Read ↗

Current Position of the Molecular Therapeutic Targets for Ovarian Clear Cell Carcinoma: A Literature ReviewSemantic proximity Read ↗

Ovarian clear cell adenocarcinoma: a continuing enigma.Semantic proximity Read ↗

Establishment and molecular characterization of a human ovarian clear cell carcinoma cell line (FDOV1).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.