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Article

Tenovin 3 induces apoptosis and ferroptosis in EGFR 19del non small cell lung cancer cells.

Scientific reports - 1 Apr 2024

Lv Sha, Pan Qianrong, Lu Weijin, Zhang Weisong, Wang Naike, Huang Lijuan, Li Lianjing, Liu Jieyao, Ma Jiamei, Li Zhan, Huang Yong, Deng Qiudi, Lei Xueping

Abstract excerpt

Epidermal growth factor receptor (EGFR) exon 19 deletion is a major driver for the drug resistance of non-small cell lung cancer (NSCLC). Identification small inhibitor capable of selectively inhibiting EGFR-19del NSCLC is a desirable strategy to overcome drug resistance in NSCLC. This study aims to screen an inhibitor for EGFR exon 19 deletion cells and explore its underlying mechanism. High through-put screen...

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Source

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Identifiers

PMID: 38561419
DOI: 10.1038/s41598-024-58499-5
PMCID: PMC10985106

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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