Article
Genetic correlations between liver fat content, metabolic health, and adiposity distribution in the Fels Longitudinal Study.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Jul 2024
Garza Ariana L, Lee Miryoung, Blangero John, Bauer Cici X, Czerwinski Stefan A, Choh Audrey C
Abstract excerpt
BACKGROUND AND AIMS: Hepatic steatosis is known to be heritable, but its genetic basis is mostly uncharacterized. Steatosis is associated with metabolic and adiposity features; recent studies hypothesize that shared genetic effects between these traits could account for some of the unexplained heritability. This study aimed to quantify these genetic associations in a family-based sample of non-Hispanic white...
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