Article
Characterization of European ancestry nonalcoholic fatty liver disease-associated variants in individuals of African and Hispanic descent.
Hepatology (Baltimore, Md.) - 1 Sept 2013
Palmer Nicholette D, Musani Solomon K, Yerges-Armstrong Laura M, Feitosa Mary F, Bielak Lawrence F, Hernaez Ruben, Kahali Bratati, Carr J Jeffrey, Harris Tamara B, Jhun Min A, Kardia Sharon L R, Langefeld Carl D, Mosley Thomas H, Norris Jill M, Smith Albert V, Taylor Herman A, Wagenknecht Lynne E, Liu Jiankang, Borecki Ingrid B, Peyser Patricia A, Speliotes Elizabeth K
Abstract excerpt
UNLABELLED: Nonalcoholic fatty liver disease (NAFLD) is an obesity-related condition affecting over 50% of individuals in some populations and is expected to become the number one cause of liver disease worldwide by 2020. Common, robustly associated genetic variants in/near five genes were identified for hepatic steatosis, a quantifiable component of NAFLD, in European ancestry individuals. Here we tested whether...
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