Article
Genome-wide Studies Reveal Genetic Risk Factors for Hepatic Fat Content.
Genomics, proteomics & bioinformatics - 3 Jul 2024
Li Yanni, van den Berg Eline H, Kurilshikov Alexander, Zhernakova Dasha V, Gacesa Ranko, Hu Shixian, Lopera-Maya Esteban A, Zhernakova Alexandra, de Meijer Vincent E, Sanna Serena, Dullaart Robin P F, Blokzijl Hans, Festen Eleonora A M, Fu Jingyuan, Weersma Rinse K
Abstract excerpt
Genetic susceptibility to metabolic associated fatty liver disease (MAFLD) is complex and poorly characterized. Accurate characterization of the genetic background of hepatic fat content would provide insights into disease etiology and causality of risk factors. We performed genome-wide association study (GWAS) on two noninvasive definitions of hepatic fat content: magnetic resonance imaging proton density fat...
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