Article
Heritability of nonalcoholic fatty liver disease.
Gastroenterology - 1 May 2009
Schwimmer Jeffrey B, Celedon Manuel A, Lavine Joel E, Salem Rany, Campbell Nzali, Schork Nicholas J, Shiehmorteza Masoud, Yokoo Takeshi, Chavez Alyssa, Middleton Michael S, Sirlin Claude B
Abstract excerpt
BACKGROUND & AIMS: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the United States. The etiology is believed to be multifactorial with a substantial genetic component; however, the heritability of NAFLD is undetermined. Therefore, a familial aggregation study was performed to test the hypothesis that NAFLD is highly heritable. METHODS: Overweight children with biopsy-proven...
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