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Article

Frequency of Fusion Inhibitor Resistance Mutations Among Therapy-Naïve HIV Patients.

AIDS research and human retroviruses - 1 Aug 2024

Ghassabi Farzaneh, Hashempour Ava, Dehghani Behzad, Hasanshahi Zahra, Khodadad Nastaran, Behizadeh Farideh, Davarpanah Mohamad Ali

Abstract excerpt

Glycoprotein 41 (gp41) of the human immunodeficiency virus type 1 (HIV-1) protein plays a critical role in membrane fusion. Gp41 binds to proteins in the plasma membrane of CD4+ T cells, particularly the T-cell antigen receptor (TCR). These findings indicate that gp41 is involved in the assembly of HIV-1 at the plasma membrane of T cells and affects the stimulation of the TCR. To control HIV-1, new inhibitors...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38553905
DOI: 10.1089/AID.2023.0102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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