Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Small-molecule HIV-1 entry inhibitors targeting gp120 and gp41: a patent review (2010-2015)

11 Jan 2017

Abstract excerpt

INTRODUCTION: It is essential to discover and develop small-molecule HIV-1 entry inhibitors with suitable pharmaceutical properties. Areas covered: We review the development of small-molecule HIV-1 entry inhibitors as evidenced in patents, patent applications, and related research articles published between 2010 and 2015. Expert opinion: HIV-1 Env gp120 and gp41 are important targets for development of HIV-1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV/AIDS Research and Interventions
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28076686
DOI: 10.1080/13543776.2017.1281249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Small-molecule HIV-1 entry inhibitors targeting gp120 and gp41: a patent review (2010-2015)PMID 28076686Read ↗

High Throughput Screening and Characterization of HIV-1 Entry Inhibitors Targeting gp41: Theories and TechniquesSemantic proximity Read ↗

Computational studies identifying entry inhibitor scaffolds targeting the Phe43 cavity of HIV-1 gp120.Semantic proximity Read ↗

Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion PeptideSemantic proximity Read ↗

Peptide fusion inhibitors targeting the HIV-1 gp41: a patent review (2009 – 2014)Semantic proximity Read ↗

ADS-J1 inhibits HIV-1 infection and membrane fusion by targeting the highly conserved pocket in the gp41 NHR-trimer.Semantic proximity Read ↗

A novel HIV-1 gp41 tripartite model for rational design of HIV-1 fusion inhibitors with improved antiviral activitySemantic proximity Read ↗

Trilobatin as an HIV ‐1 entry inhibitor targeting the HIV ‐1 Gp41 envelopeSemantic proximity Read ↗

The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding SiteSemantic proximity Read ↗

Identification of a Critical Motif for the Human Immunodeficiency Virus Type 1 (HIV-1) gp41 Core Structure: Implications for Designing Novel Anti-HIV Fusion InhibitorsSemantic proximity Read ↗

Biochemistry and Biophysics of HIV-1 gp41 - Membrane Interactions and Implications for HIV-1 Envelope Protein Mediated Viral-Cell Fusion and Fusion Inhibitor DesignSemantic proximity Read ↗

N- and C-domains of HIV-1 gp41: mutation, structure and functions.Semantic proximity Read ↗

Design of a highly potent HIV-1 fusion inhibitor targeting the gp41 pocket.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.