Article
Resistance to enfuvirtide, the first HIV fusion inhibitor.
The Journal of antimicrobial chemotherapy - 1 Aug 2004
Greenberg Michael L, Cammack Nick
Abstract excerpt
Fusion inhibitors are a new class of antiretroviral drugs (ARVs) for the treatment of human immunodeficiency virus infection. Enfuvirtide is the first in this class to reach market approval. Fusion inhibitors block the last step in the three-step viral entry process consisting of attachment, co-receptor binding and fusion, thereby preventing viral capsid entry into the host cell. Enfuvirtide has a unique...
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