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Article

Donor genetic determinant of thymopoiesis, rs2204985, and stem cell transplantation outcome in a multipopulation cohort.

Human immunology - 1 May 2024

Nihtilä Julia, Salmenniemi Urpu, Itälä-Remes Maija, Crossland Rachel E, Gallardo David, Bogunia-Kubik Katarzyna, Łacina Piotr, Bieniaszewska Maria, Giebel Sebastian, Hyvärinen Kati, Kekäläinen Eliisa, Ritari Jarmo, Partanen Jukka

Abstract excerpt

BACKGROUND: A genetic polymorphism, rs2204985, has been reported to be associated with the diversity of T-cell antigen receptor repertoire and TREC levels, reflecting the function of the thymus. As the thymus function can be assumed to be an important factor regulating the outcome of stem cell transplantation (SCT), it was of great interest that rs2204985 showed a genetic association to disease-free and overall...

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PMID: 38553383
DOI: 10.1016/j.humimm.2024.110791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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