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Article

Prognostic value of pretransplantation host thymic function in HLA-identical sibling hematopoietic stem cell transplantation

17 Nov 2004

Abstract excerpt

Thymic function is critical for immune reconstitution after hematopoietic stem cell transplantation (HSCT). We evaluated recipient thymic function before HSCT by quantifying T-cell receptor excision circles (TRECs) in pretransplantation peripheral blood lymphocytes from 102 patients who received HSCs from an HLA-identical sibling for malignant (n = 87) or nonmalignant diseases (n = 15). Median TREC value before...

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PMID: 15546951
DOI: 10.1182/blood-2004-04-1667

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