A polymorphism in the TYMP gene is associated with the outcome of HLA-identical sibling allogeneic stem cell transplantation.

doi:10.1002/ajh.23523

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Article

A polymorphism in the TYMP gene is associated with the outcome of HLA-identical sibling allogeneic stem cell transplantation.

American journal of hematology - 1 Oct 2013

Guillem Vicent, Hernández-Boluda Juan Carlos, Gallardo David, Buño Ismael, Bosch Anna, Martínez-Laperche Carolina, de la Cámara Rafael, Brunet Salut, Martin Carmen, Nieto José B, Martínez Carmen, Pérez Ariadna, Montoro Juan, Garcia-Noblejas Ana, Solano Carlos

Abstract excerpt

Thymidine phosphorylase (TYMP), an enzyme involved in nucleotide synthesis, has been implicated in critical biological processes such as DNA replication, protection against mutations, and tissue repair. In this work, we retrospectively evaluated the influence of a polymorphism in the TYMP gene (rs112723255; G/A) upon the outcome of 448 patients subjected to allogeneic stem cell transplantation (allo-SCT) from an...

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Identifiers

PMID: 23813863
DOI: 10.1002/ajh.23523

Genes

TYMP
SCT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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