Article
Genetic and Phenotypic Features of Schizophrenia in the UK Biobank.
JAMA psychiatry - 1 Jul 2024
Legge Sophie E, Pardiñas Antonio F, Woolway Grace, Rees Elliott, Cardno Alastair G, Escott-Price Valentina, Holmans Peter, Kirov George, Owen Michael J, O'Donovan Michael C, Walters James T R
Abstract excerpt
Importance: Large-scale biobanks provide important opportunities for mental health research, but selection biases raise questions regarding the comparability of individuals with those in clinical research settings. Objective: To compare the genetic liability to psychiatric disorders in individuals with schizophrenia in the UK Biobank with individuals in the Psychiatric Genomics Consortium (PGC) and to compare...
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