Article
Natural history of clonal haematopoiesis seen in real-world haematology settings.
British journal of haematology - 1 May 2024
Patel Shyam A, Gerber William K, Zheng Rena, Khanna Shrinkhala, Hutchinson Lloyd, Abel Gregory A, Cerny Jan, DaSilva Brandon A, Zhang Tian Y, Ramanathan Muthalagu, Khedr Salwa, Selove William, Woda Bruce, Miron Patricia M, Higgins Anne W, Gerber Jonathan M
Abstract excerpt
Recursive partitioning of healthy consortia led to the development of the Clonal Hematopoiesis Risk Score (CHRS) for clonal haematopoiesis (CH); however, in the practical setting, most cases of CH are diagnosed after patients present with cytopenias or related symptoms. To address this real-world population, we characterize the clinical trajectories of 94 patients with CH and distinguish CH harbouring canonical...
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