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Article

Genetically predicted high serum sex hormone-binding globulin levels are associated with lower ischemic stroke risk: A sex-stratified Mendelian randomization study.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Jun 2024

Sun Wei, Wang Yuan, Li Cancan, Yao Xuefan, Wu Xiao, He Aini, Zhao Benke, Huang Xiaoqin, Song Haiqing

Abstract excerpt

OBJECTIVE: Cross-sectional and cohort studies have found insufficient evidence of a causal relationship between sex hormone-binding globulin and ischemic stroke, only associations. Here, we performed a sex-stratified, bidirectional, two-sample Mendelian randomization analysis to evaluate whether a causal relationship exists between sex hormone-binding globulin and ischemic stroke. METHODS: Single-nucleotide...

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PMID: 38522757
DOI: 10.1016/j.jstrokecerebrovasdis.2024.107686

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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