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Carriers of HLA-DRB1*04:05 have a better clinical response to abatacept in rheumatoid arthritis

14 Sept 2023

Abstract excerpt

HLA-DRB1 shared epitope risk alleles are the strongest genetic risk factors for rheumatoid arthritis (RA) and potential biomarkers for treatment response to biological disease-modifying antirheumatic drugs (bDMARDs). This study aimed to investigate the association between treatment response and individual HLA-DRB1 alleles in RA patients receiving different bDMARDs. We recruited 106 patients with active RA who had...

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PMID: 37709837
DOI: 10.1038/s41598-023-42324-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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