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The E3 ligase TRIM7 suppresses the tumorigenesis of gastric cancer by targeting SLC7A11

20 Mar 2024

Abstract excerpt

Tripartite motif-containing protein 7 (TRIM7), as an E3 ligase, plays an important regulatory role in various physiological and pathological processes. However, the role of TRIM7 in gastric cancer (GC) is still undefined. Our study detected the expression of TRIM7 in clinical specimens and investigated the regulatory effect and molecular mechanism of TRIM7 on GC progression through in vitro and in vivo...

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PMID: 38509147
DOI: 10.1038/s41598-024-56746-3

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