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RNF128 promotes gastric cancer progression by inhibiting autophagy-dependent ferroptosis through Beclin1 ubiquitination

19 Apr 2025

Abstract excerpt

As an important protein post-translational modification process, ubiquitination plays an indispensable role in the regulation of gastric cancer (GC) occurrence and development. And recent studies have demonstrated that this modification is closely related to regulated cell death. This suggests that our therapeutic approach to inhibit the malignant progression of GC by regulating the intracellular death mode...

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Share to Epigenetics and DNA Methylation
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PMID: 40253377
DOI: 10.1038/s41420-025-02488-8

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