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Article

Estimating causality between smoking and abdominal obesity by Mendelian randomization

20 Mar 2024

Abstract excerpt

Abstract Background and aims Smokers tend to have a lower body weight than non‐smokers, but also more abdominal fat. It remains unclear whether or not the relationship between smoking and abdominal obesity is causal. Previous Mendelian randomization (MR) studies have investigated this relationship by relying upon a single genetic variant for smoking heaviness. This approach is sensitive to pleiotropic effects and...

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PMID: 38509034
DOI: 10.1111/add.16454

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