Article
Is smoking heaviness causally associated with alcohol use? A Mendelian randomization study in four European cohorts.
International journal of epidemiology - 1 Aug 2018
Taylor Michelle, Rode Line, Bjørngaard Johan, Taylor Amy E, Bojesen Stig E, Åsvold Bjørn O, Gabrielsen Maiken E, Lewis Glyn, Nordestgaard Børge G, Romundstad Pål R, Hickman Matthew, Munafò Marcus R
Abstract excerpt
Background: Observational studies have shown that tobacco and alcohol use co-occur, but it is not clear whether this relationship is causal. Methods: Using data from the Avon Longitudinal Study of Parents and Children (ALSPAC) and UK Biobank, we used observational methods to test the hypothesis that smoking heaviness increases alcohol consumption. Mendelian randomization (MR) analyses were then used to test the...
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