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Article

Causal effects from tobacco smoking initiation on obesity-related traits: a Mendelian randomization study.

International journal of obesity (2005) - 1 Dec 2023

Park Sehoon, Kim Seong Geun, Lee Soojin, Kim Yaerim, Cho Semin, Kim Kwangsoo, Kim Yong Chul, Han Seung Seok, Lee Hajeong, Lee Jung Pyo, Joo Kwon Wook, Lim Chun Soo, Kim Yon Su, Kim Dong Ki

Abstract excerpt

BACKGROUND: There is a widespread notion that tobacco smoking controls weight based on the appetite suppressive effect of nicotine. However, the causal relationship between smoking initiation and obesity-related traits in the general population are unclear. METHODS: This Mendelian randomization analysis utilized 378 genetic variants associated with tobacco smoking initiation (usually in adolescence or young...

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PMID: 37634025
DOI: 10.1038/s41366-023-01371-9

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