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SLC40A1 in iron metabolism, ferroptosis, and disease: A review

20 Mar 2024

Abstract excerpt

Solute carrier family 40 member 1 (SLC40A1) plays an essential role in transporting iron from intracellular to extracellular environments. When SLC40A1 expression is abnormal, cellular iron metabolism becomes dysregulated, resulting in an overload of intracellular iron, which induces cell ferroptosis. Numerous studies have confirmed that ferroptosis is closely associated with the development of many diseases....

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PMID: 38508867
DOI: 10.1002/wsbm.1644

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