Iron homeostasis: transport, metabolism, and regulation.

Abstract excerpt

PURPOSE OF REVIEW: Iron is essential for normal cellular function and many diseases result from disturbances in iron homeostasis. This review describes some of the recent key advances in iron transport and its regulation, how this relates to iron-related disorders, and emerging therapies for these diseases. RECENT FINDINGS: The iron-regulatory hormone hepcidin and its target, the iron exporter ferroportin (FPN),...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Anemia, Iron-Deficiency
• Share to Erythropoiesis
• Share to Ferroportin