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Anaplastic thyroid cancer spheroids as preclinical models to test therapeutics

19 Mar 2024

Abstract excerpt

Abstract Anaplastic thyroid cancer (ATC) is the most aggressive thyroid cancer. Despite advances in tissue culture techniques, a robust model for ATC spheroid culture is yet to be developed. In this study, we created an efficient and cost-effective 3D tumor spheroids culture system from human ATC cells and existing cell lines that better mimic patient tumors and that can enhance our understanding of in vivo...

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PMID: 38500204
DOI: 10.1186/s13046-024-03009-8

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