Article
A novel 193-plex MPS panel integrating STRs and SNPs highlights the application value of forensic genetics in individual identification and paternity testing.
Human genetics - 1 Mar 2024
Liu Xueyuan, Yang Chengliang, Chen Xiaohui, Han Xiaolong, Liu Hong, Zhang Xingkun, Xu Quyi, Yang Xingyi, Liu Changhui, Chen Ling, Liu Chao
Abstract excerpt
Massively parallel sequencing (MPS) has emerged as a promising technology for targeting multiple genetic loci simultaneously in forensic genetics. Here, a novel 193-plex panel was designed to target 28 A-STRs, 41 Y-STRs, 21 X-STRs, 3 sex-identified loci, and 100 A-SNPs by employing a single-end 400 bp sequencing strategy on the MGISEQ-2000™ platform. In the present study, a series of validations and sequencing of...
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