Massively parallel sequencing of 25 autosomal STRs including SE33 in four population groups for forensic applications.

Abstract excerpt

The introduction of massively parallel sequencing (MPS) in forensic investigation enables sequence-based large-scale multiplexing beyond size-based analysis using capillary electrophoresis (CE). For the practical application of MPS to forensic casework, many population studies have provided sequence data for autosomal short tandem repeats (STRs). However, SE33, a highly polymorphic STR marker, has little...

Topics

• Electrophoresis, Capillary
• Forensic Genetics
• Gene Frequency
• High-Throughput Nucleotide Sequencing
• Humans
• Microsatellite Repeats
• Polymerase Chain Reaction
• Polymorphism, Single Nucleotide
• Population Groups