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Sequence polymorphisms of forensic Y-STRs revealed by a 68-plex in-house massively parallel sequencing panel.

Forensic science international. Genetics - 1 Jul 2022

Yang Kai-Run, Miao Lei, Kang Ke-Lai, Feng Yao-Sen, Ji An-Quan, Zhang Chi, Guo Li-Liang, Gao Yue, Wei Mei-Tian, Ye Jian, Wu Jian, Wang Le

Abstract excerpt

Sequence polymorphisms of Y chromosome short tandem repeat (Y-STR) markers can be unveiled using next generation sequencing (NGS). Compared to capillary electrophoresis, NGS has the advantage of distinguishing between some alleles of the same length. Here, a 68-plex in-house panel covering 67 Y-STR loci and the sex determinant Amelogenin locus, was developed. The accuracy of this panel was 100% concordant with...

Topics

Alleles
Chromosomes, Human, Y
DNA Fingerprinting
High-Throughput Nucleotide Sequencing
Humans
Microsatellite Repeats
Polymorphism, Single Nucleotide

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 35660778
DOI: 10.1016/j.fsigen.2022.102727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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