Article
DNA array analysis for red blood cell antigens facilitates the transfusion support with antigen-matched blood in patients with sickle cell disease.
Vox sanguinis - 1 Aug 2009
Ribeiro K R, Guarnieri M H, da Costa D C, Costa F F, Pellegrino J, Castilho L
Abstract excerpt
BACKGROUND: Blood samples from patients with sickle cell disease (SCD) present to transfusion service with numerous antibodies, making the searching for compatible red blood cells (RBC) a challenge. To overcome this problem we developed an effective strategy to meet needs of supplying RBC-compatible units to SCD patients using DNA arrays. METHODS: We selected DNA samples from 144 SCD patients with multiple...
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