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Article

Roles for epithelial integrin α3β1 in regulation of the microenvironment during normal and pathological tissue remodeling

18 Mar 2024

Abstract excerpt

Integrin receptors for the extracellular matrix activate intracellular signaling pathways that are critical for tissue development, homeostasis, and regeneration/repair, and their loss or dysregulation contributes to many developmental defects and tissue pathologies. This review will focus on tissue remodeling roles for integrin α3β1, a receptor for laminins found in the basement membranes (BMs) that underlie...

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PMID: 38497112
DOI: 10.1152/ajpcell.00128.2024

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