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Article

A Skin-depth Analysis of Integrins: Role of the Integrin Network in Health and Disease

8 Nov 2013

Abstract excerpt

In the skin epidermis, adhesion to the underlying basement membrane is mediated through trans-membrane integrin receptors. In addition to a structural role, integrins can signal in a bi-directional manner though the membrane and thus play a crucial role in cell adhesion, migration, proliferation, and differentiation. In this review we will discuss the role of integrins and their network of partner proteins in...

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Identifiers

PMID: 24205983
DOI: 10.3109/15419061.2013.854334

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