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Article

Regulation of barrier immunity and homeostasis by integrin‐mediated transforming growth factor <i>β</i> activation

3 Dec 2019

Abstract excerpt

Summary Transforming growth factor β (TGF‐ β ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. Various cell types secrete TGF‐ β , but always as an inactive complex. Hence, for TGF‐ β to function, this latent complex must somehow be activated. Work in recent years has highlighted a critical...

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PMID: 31792952
DOI: 10.1111/imm.13162

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