Article
Exercise, weight loss, and changes in body composition in mice: phenotypic relationships and genetic architecture.
Physiological genomics - 24 Feb 2011
Kelly Scott A, Nehrenberg Derrick L, Hua Kunjie, Garland Theodore, Pomp Daniel
Abstract excerpt
The regulation of body weight and composition is complex, simultaneously affected by genetic architecture, the environment, and their interactions. We sought to analyze the complex phenotypic relationships between voluntary exercise, food consumption, and changes in body weight and composition and simultaneously localize quantitative trait loci (QTL) controlling these traits. A large (n = 815) murine advanced...
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