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Article

DeePNAP: A Deep Learning Method to Predict Protein-Nucleic Acid Binding Affinity from Their Sequences.

Journal of chemical information and modeling - 25 Mar 2024

Pandey Uddeshya, Behara Sasi M, Sharma Siddhant, Patil Rachit S, Nambiar Souparnika, Koner Debasish, Bhukya Hussain

Abstract excerpt

Predicting the protein-nucleic acid (PNA) binding affinity solely from their sequences is of paramount importance for the experimental design and analysis of PNA interactions (PNAIs). A large number of currently developed models for binding affinity prediction are limited to specific PNAIs while also relying on the sequence and structural information of the PNA complexes for both training and testing, and also as...

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PMID: 38458968
DOI: 10.1021/acs.jcim.3c01151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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