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Article

The causal association between circulating cytokines with the risk of frailty and sarcopenia under the perspective of geroscience.

Frontiers in endocrinology - 1 Jan 2024

Wang Congzhi, Wang Jiazhi, Wan Rui, Kurihara Hiroshi, Wang Min

Abstract excerpt

Introduction: Circulating cytokines were considered to play a critical role in the initiation and propagation of sarcopenia and frailty from observational studies. This study aimed to find the casual association between circulating cytokines and sarcopenia and frailty from a genetic perspective by two-sample Mendelian randomization (MR) analysis. Methods: Data for 41 circulating cytokines were extracted from the...

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Identifiers

PMID: 38505750
DOI: 10.3389/fendo.2024.1293146
PMCID: PMC10948489

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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