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Article

Causal relationship of interleukin-6 and its receptor on sarcopenia traits using mendelian randomization.

Nutrition journal - 15 May 2024

Chen Baixing, Li Shaoshuo, Lin Shi, Dong Hang

Abstract excerpt

BACKGROUND: Previous research has extensively examined the role of interleukin 6 (IL-6) in sarcopenia. However, the presence of a causal relationship between IL-6, its receptor (IL-6R), and sarcopenia remains unclear. METHOD: In this study, we utilized summary-level data from genome-wide association studies (GWAS) focused on appendicular lean mass (ALM), hand grip strength, and walking pace. Single nucleotide...

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Source

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Identifiers

PMID: 38750566
DOI: 10.1186/s12937-024-00958-w
PMCID: PMC11094953

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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