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Article

frDriver: A Functional Region Driver Identification for Protein Sequence.

IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000

Lu Xinguo, Wang Xinyu, Ding Li, Li Jinxin, Gao Yan, He Keren

Abstract excerpt

Identifying cancer drivers is a crucial challenge to explain the underlying mechanisms of cancer development. There are many methods to identify cancer drivers based on the single mutation site or the entire gene. But they ignore a large number of functional elements with medium in size. It is hypothesized that mutations occurring in different regions of the protein sequence have different effects on the...

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PMID: 32870797
DOI: 10.1109/TCBB.2020.3020096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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