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Article

Statin Initiation and Risk of Incident Alzheimer Disease and Cognitive Decline in Genetically Susceptible Older Adults.

Neurology - 9 Apr 2024

Rajan Kumar B, Mcaninch Elizabeth A, Wilson Robert S, Dhana Anisa, Evans-Lacko Sara, Evans Denis A

Abstract excerpt

BACKGROUND AND OBJECTIVES: The association of statin initiation with incident Alzheimer disease (AD) dementia and cognitive decline by the APOE ε4 allele is unknown. Our objective was to examine whether the association of statin initiation with incident AD dementia and cognitive decline differs by the APOE ε4 allele. METHODS: This population-based longitudinal cohort study was conducted in 4 urban communities in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38447103
DOI: 10.1212/WNL.0000000000209168
PMCID: PMC11770690

Genes

APOE

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