Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Age-varying association between statin use and incident Alzheimer's disease.

Journal of the American Geriatrics Society - 1 Jul 2010

Li Ge, Shofer Jane B, Rhew Isaac C, Kukull Walter A, Peskind Elaine R, McCormick Wayne, Bowen James D, Schellenberg Gerard D, Crane Paul K, Breitner John C S, Larson Eric B

Abstract excerpt

OBJECTIVES: To determine whether risk reduction of statins for Alzheimer's disease (AD) varies by age or presence of apolipoprotein E (APOE) epsilon4 allele. DESIGN: A cohort of cognitively intact elderly participants was assessed biennially for dementia and AD. SETTING: Community based. PARTICIP...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Aged, 80 and over
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein E4

Share to Cohort Studies

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Share to Incidence

Share to Proportional Hazards Models

Source

Open in PubMed Open full text

Identifiers

PMID: 20533968
DOI: 10.1111/j.1532-5415.2010.02906.x
PMCID: PMC3176730

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20533968-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Age-varying association between statin use and incident Alzheimer's disease.PMID 20533968Read ↗

Statin Initiation and Risk of Incident Alzheimer Disease and Cognitive Decline in Genetically Susceptible Older Adults.Semantic proximity Read ↗

Sex and APOE Genotype Differences Related to Statin Use in The Aging PopulationSemantic proximity Read ↗

Sex and APOE genotype differences related to statin use in the aging populationSemantic proximity Read ↗

Association of statins use and genetic susceptibility with incidence of Alzheimer's diseaseSemantic proximity Read ↗

Association of statin use with cognitive decline in elderly African Americans.Semantic proximity Read ↗

Apolipoprotein E ε4 allele interacts with sex and cognitive status to influence all-cause and cause-specific mortality in U.S. older adults.Semantic proximity Read ↗

Apolipoprotein E genotypes and the incidence of Alzheimer's disease among persons aged 75 years and older: variation by use of antihypertensive medication?Semantic proximity Read ↗

Identifying drug repositioning candidates for age-related outcomes in the Danish health registriesSemantic proximity Read ↗

Lipid-lowering agents and the risk of cognitive impairment that does not meet criteria for dementia, in relation to apolipoprotein E status.Semantic proximity Read ↗

Association of blood lipids, atherosclerosis and statin use with dementia after strokeSemantic proximity Read ↗

Effect of initiating an ARB- versus ACEI-based regimen on dementia risk, a target trial emulation of 2.5 million US VeteransSemantic proximity Read ↗

Decreasing hazards of Alzheimer's disease with the use of antidepressants: mitigating the risk of depression and apolipoprotein E.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.