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Genetic predisposition to lymphomas: Overview of rare syndromes and inherited familial variants.

Mutation research. Reviews in mutation research - 1 Jan 2000

Szmyd Bartosz, Mlynarski Wojciech, Pastorczak Agata

Abstract excerpt

Approximately 10 % of malignancies occur in carriers of germline mutations predisposing to cancer. A high risk of developing lymphomas has been noted in many primary immunodeficiencies, including DNA repair disorders. Moreover, implementation of next-generation sequencing has recently enabled to uncover rare genetic variants predisposing patients to lymphoid neoplasms. Some patients harboring inherited...

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PMID: 34893151
DOI: 10.1016/j.mrrev.2021.108386

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