Article
Association between germline pathogenic variants in cancer-predisposing genes and lymphoma risk.
Cancer science - 1 Nov 2022
Usui Yoshiaki, Iwasaki Yusuke, Matsuo Keitaro, Endo Mikiko, Kamatani Yoichiro, Hirata Makoto, Sugano Kokichi, Yoshida Teruhiko, Matsuda Koichi, Murakami Yoshinori, Maeda Yoshinobu, Nakagawa Hidewaki, Momozawa Yukihide
Abstract excerpt
The application of advanced molecular technology has significantly expanded lymphoma classification, allowing risk stratification and treatment optimization. Limited evidence suggests the presence of a genetic predisposition in lymphoma, indicating the potential for better individualized clinical management based on a novel lymphoma classification. Herein, we examined the impact of germline pathogenic variants in...
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