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Structural Brain Correlates of Sleep Microstructure in Spinocerebellar Ataxia Type 2 and its Role on Clinical Phenotype.

Cerebellum (London, England) - 1 Oct 2024

Rodríguez-Labrada Roberto, Canales-Ochoa Nalia, Galicia-Polo Maria de Lourdes, Cruz-Rivas Edilia, Romanzetti Sandro, Peña-Acosta Arnoy, Estupiñán-Rodríguez Annelié, Vázquez-Mojena Yaimeé, Dogan Imis, Auburger Georg, Reetz Kathrin, Velázquez-Pérez Luis

Abstract excerpt

The influence of brain atrophy on sleep microstructure in Spinocerebellar Ataxias (SCAs) has not been extensively explored limiting the use of these sleep traits as surrogate biomarkers of neurodegeneration and clinical phenotype. The objective of the study is to explore the relationship between sleep microstructure and brain atrophy in SCA2 and its role in the clinical phenotype. Fourteen SCA2 mutation carriers...

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PMID: 38438827
DOI: 10.1007/s12311-024-01674-1

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