Article
Extreme restructuring of cis-regulatory regions controlling a deeply conserved plant stem cell regulator.
PLoS genetics - 1 Mar 2024
Ciren Danielle, Zebell Sophia, Lippman Zachary B
Abstract excerpt
A striking paradox is that genes with conserved protein sequence, function and expression pattern over deep time often exhibit extremely divergent cis-regulatory sequences. It remains unclear how such drastic cis-regulatory evolution across species allows preservation of gene function, and to what extent these differences influence how cis-regulatory variation arising within species impacts phenotypic change....
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