Solanum pan-genetics reveals paralogues as contingencies in crop engineering.

doi:10.1038/s41586-025-08619-6

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Article

Solanum pan-genetics reveals paralogues as contingencies in crop engineering.

Nature - 1 Apr 2025

Benoit Matthias, Jenike Katharine M, Satterlee James W, Ramakrishnan Srividya, Gentile Iacopo, Hendelman Anat, Passalacqua Michael J, Suresh Hamsini, Shohat Hagai, Robitaille Gina M, Fitzgerald Blaine, Alonge Michael, Wang Xingang, Santos Ryan, He Jia, Ou Shujun, Golan Hezi, Green Yumi, Swartwood Kerry, Karavolias Nicholas G, Sierra Gina P, Orejuela Andres, Roda Federico, Goodwin Sara, McCombie W Richard, Kizito Elizabeth B, Gagnon Edeline, Knapp Sandra, Särkinen Tiina E, Frary Amy, Gillis Jesse, Van Eck Joyce, Schatz Michael C, Lippman Zachary B

Abstract excerpt

Pan-genomics and genome-editing technologies are revolutionizing breeding of global crops1,2. A transformative opportunity lies in exchanging genotype-to-phenotype knowledge between major crops (that is, those cultivated globally) and indigenous crops (that is, those locally cultivated within a circumscribed area)3-5 to enhance our food system. However, species-specific genetic variants and their interactions...

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PMID: 40044854
DOI: 10.1038/s41586-025-08619-6
PMCID: PMC11964936

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