Article
Threshold-dependent transcriptional discrimination underlies stem cell homeostasis.
Proceedings of the National Academy of Sciences of the United States of America - 11 Oct 2016
Perales Mariano, Rodriguez Kevin, Snipes Stephen, Yadav Ram Kishor, Diaz-Mendoza Mercedes, Reddy G Venugopala
Abstract excerpt
Transcriptional mechanisms that underlie the dose-dependent regulation of gene expression in animal development have been studied extensively. However, the mechanisms of dose-dependent transcriptional regulation in plant development have not been understood. In Arabidopsis shoot apical meristems, WUSCHEL (WUS), a stem cell-promoting transcription factor, accumulates at a higher level in the rib meristem and at a...
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