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Article

Two synonymous single-nucleotide polymorphisms promoting fluoroquinolone resistance of Escherichia coli in the environment.

Journal of hazardous materials - 5 May 2024

Zhong Tairan, Wu Haiming, Hu Jiehua, Liu Yun, Zheng Yundan, Li Nan, Sun Zhenghua, Yin Xing-Feng, He Qing-Yu, Sun Xuesong

Abstract excerpt

Single-nucleotide polymorphism (SNP) is one of the core mechanisms that respond to antibiotic resistance of Escherichia coli (E. coli), which is a major issue in environmental pollution. A specific type of SNPs, synonymous SNPs, have been generally considered as the "silent" SNPs since they do not change the encoded amino acid. However, the impact of synonymous SNPs on mRNA splicing, nucleo-cytoplasmic export,...

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PMID: 38432089
DOI: 10.1016/j.jhazmat.2024.133849

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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