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Article

Novel Conserved Genotypes Correspond to Antibiotic Resistance Phenotypes of E. coli Clinical Isolates.

PloS one - 1 Jan 2013

Swick Michelle C, Evangelista Michael A, Bodine Truston J, Easton-Marks Jeremy R, Barth Patrick, Shah Minita J, Bormann Chung Christina A, Stanley Sarah, McLaughlin Stephen F, Lee Clarence C, Sheth Vrunda, Doan Quynh, Hamill Richard J, Steffen David, Becnel Lauren B, Sucgang Richard, Zechiedrich Lynn

Abstract excerpt

Current efforts to understand antibiotic resistance on the whole genome scale tend to focus on known genes even as high throughput sequencing strategies uncover novel mechanisms. To identify genomic variations associated with antibiotic resistance, we employed a modified genome-wide association study; we sequenced genomic DNA from pools of E. coli clinical isolates with similar antibiotic resistance phenotypes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23824211
DOI: 10.1371/journal.pone.0065961
PMCID: PMC3688849

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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